oldenlandia diffusa for lung cancer

2019 Jan-Dec;18:1534735419827079. doi: 10.1177/1534735419827079. The combination of Scutellaria barbata and Oldenlandia diffusa can enhance the anticancer effect of each other, which is the key point of anticancer herbs. © 2020 Memorial Sloan Kettering Cancer Center, Gerstner Sloan Kettering Graduate School of Biomedical Sciences, Integrative Medicine at Home Membership Program, A comparable, chemical and pharmacological analysis of the traditional Chinese medicinal herbs, [Immunomodulatory activity and anti-tumor activity of. More research is necessary to confirm whether this herb can be used safely and effectively for any condition in humans. In his quest to battle lung cancer, the leading cause of cancer deaths in both men and women, Dr. Shao studied the effects of the Chinese herb oldenlandia diffusa. Donate today. Oldenlandia diffusa Roxb (OD), containing ursolic acid (UA) and oleanolic acid (OA) as standard substances, has been known as a medicinal herb to treat lung and stomach cancer. Oldenlandia diffusa extract was given at the dose level of 5 g raw material/kg on Days 3-12 by oral gavage and the extent of lung metastases were examined on Day 14. This Web site is not to be used as a substitute for medical advice, diagnosis or treatment of any health condition or problem. Memorial Sloan Kettering Cancer Center makes no warranties nor express or implied representations whatsoever regarding the accuracy, completeness, timeliness, comparative or controversial nature, or usefulness of any information contained or referenced on this Web site. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. USA.gov. The aim of this study was to investigate the effects of OD extracts on breast cancer cell proliferation. Laboratory studies suggest that this herb may inhibit the growth of cancer cells and stimulate the immune system to destroy or engulf tumor cells. com or write us here. Researchers found no antiproliferative effect of the methanol extracts from O. diffusa, while the chloroform extracts exhibited slightly antiproliferative effects. Oldenlandia diffusa(OD) is a well-known traditional Chinese medicine, which is used to prevent and treat many disorders, especially cancers. Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin. Likewise, Astragalus membranaceus , Podophyllum hexandrum , Podophyllum petaton , and Arctium lappa are commonly used all around the world to treat breast cancer. Chinese researchers have conducted such clinical trials for decades and believe the evidence supports the use of Chinese herbs in cancer care. Studies conducted in vitro and in animals suggest that O. diffusa possesses anticancer and chemopreventive properties (2) (3) (4) (5) (6). This Web site — Information About Herbs, Botanicals and Other Products — is for general health information only. Meditation. Memorial Sloan Kettering does not assume any risk whatsoever for your use of this website or the information contained herein. Radiation therapy is one of the many therapies available as of 2011 to battle cancer 1 2 3. The water extract of the raw herb Oldenlandia diffusa was used in this study. Suitable for: light (sandy), medium (loamy) and heavy (clay) soils. Conclusions: It is used for treating for a variety of conditions including cancer and viral infections like hepatitis. Two similar species – Corymbosa LAM and Oldenlandia tenelliflora BL – are commonly used as substitutes for Herba Oldenlandiae (the powdered form of O. diffusa) (10). Results: The extract exhibited a strong antiproliferative activity against all cancer cell lines tested. This exploratory proposal, in response to the PA-06-400, is developed to conduct preclinical studies to demonstrate efficacy of the Chinese herb Oldenlandia diffusa (OD) for prostate cancer treatment. Oldenlandia diffusa extract was given at the dose level of 5 g raw material/kg on Days 3-12 by oral gavage and the extent of lung metastases were examined on Day 14. Learn More. COVID-19 is an emerging, rapidly evolving situation. A Network Pharmacology Approach to Uncover the Multiple Mechanisms of. However, the effect of OD on ovarian cancer is uncertain. Ji S, Fattahi A, Raffel N, Hoffmann I, Beckmann MW, Dittrich R, Schrauder M. Eur J Med Res. Human data are lacking. Antioxidant effect of aqueous extract of four plants with therapeutic potential on gynecological diseases; Semen persicae, Leonurus cardiaca, Hedyotis diffusa, and Curcuma zedoaria. Oldenlandia diffusa has shown anticancer effects in lab studies, but human data are lacking.O. The concentrations of growth inhibition at 50% (IC(50)) ranged from 7 to 25 mg raw material/ml after 48-hour treatment. The species is hermaphrodite (has both male and female organs). Canine cancer is similar to human cancer in that it typically progresses through a series of stages, from I to V. In addition to its stages, cancer is defined by grades, which indicate how aggressively the disease is behaving within the dog. It is used in traditional Chinese medicine (TCM) for the treatment of liver diseases, snake bites, and tumors. NIH Epub 2004 Dec 28. Clipboard, Search History, and several other advanced features are temporarily unavailable. Another useful herb is the Oldenlandia Diffusa which is extensively used in modern Chinese practice. Spreading Hedyotis (Hedyotis diffusa or Oldenlandia diffusa) Known in China as ‘snake needle grass’ or ‘white flower snake-tongue grass’, Hedyotis diffusa or Oldenlandia diffusa (spreading hedyotis) has been used as an anticancer herb for several thousand years and is one of the most renowned herbs prescribed for cancer treatment in Chinese traditional medicine. Oral administration of the herbal extract effectively reduced B16-F10 cell growth in the lungs of C57Bl/j mice with a 70% reduction in lung metastases (p < 0.001). Licorice (Gan Cao in Chinese) diffusa is an herb found in East Asia and Southern China. Many Chinese canc… Microscopic examination and DNA ladder analysis were carried out to determine the pro-apoptotic effect of the extract. Abstract. Oldenlandia diffusa (snake needle grass): It is believed to kill lung cancer cells; Asparagus root: It is believed to kill and prevent lung cancer cells; As a rule, it is not harmful to take herbal supplements along with your regular treatments for lung cancer. Hedyotis Diffusa is a weed. Poria is a medicinal mushroom that helps heal many ailments. Furthermore, there was a significant inhibition of lung metastases in the animal model with no noticeable adverse effects. Any questions regarding your own health should be addressed to your own physician or other healthcare provider. J Ethnopharmacol. NLM Hedyotis diffusa or Oldenlandia diffusa (spreading hedyotis) is one of the most commonly used anticancer herbs. induces apoptosis in human lung adenocarcinoma A549 and human breast cancer MCF-7 cell lines. It has immune-modulating activity and works to kill tumor cells. It is in flower from August to September. However, its role in osteosarcoma has not been well understood. Health-related information changes frequently and therefore information contained on this Web site may be outdated, incomplete or incorrect. 2007;26 Suppl 2:1-50. doi: 10.1080/10915810701351186. However, computed tomography revealed multiple lung nodules. We prescribed crude drugs with anti-cancer effects, including Scutellaria barbata and Oldenlandia diffusa. Bai Hua She She Cao is also known as Snake Needle Grass, Spreading Hedyotis, Oldenlandia Diffusa, or Hedyotis Diffusa, which is an annual herb belonging to the family Rubiaceae. Results: 2020 Apr 21;11:492. doi: 10.3389/fphar.2020.00492. 2017 Nov 25;22(1):50. doi: 10.1186/s40001-017-0293-6. Animal studies attribute anti-inflammatory activity to inhibition of tumor necrosis factor (TNF)-α, interleukin (IL)-6, and prostaglandin E2 (PGE2) (13). Oldenlandia diffusa is a well known medicinal plant that is used in Asia to treat hepatitis, tonsillitis, and malignant tumors of the liver, lung and stomach. 28 November, 2018. OD has been used in folk Chinese medicine as anti-cancer agent. Users of this Web site should not rely on information provided on this Web site for their own health problems. It contains flavones, anthraquinones, polysaccharides, and … Ursolic acid also showed anti-inflammatory effects in mice with rheumatoid arthritis (9). Oldenlandia diffusa is a ANNUAL growing to 0.3 m (1ft) by 0.3 m (1ft in). Quality control issues have been reported. Use of this Web site does not create an expressed or implied physician-patient relationship. Oldenlandia diffusa, also called snake-needle grass or Bai Hua She She Cao, has been used in traditional Chinese medicine for treating a variety of conditions, namely cancer and viral infections such as hepatitis 1 2. 50 mg/mL well understood augment macrophage oxidative burst and inhibit tumor growth treating! 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